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SCHISTOSOMIASIS

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Key takeaways

Science and Nature

Disease and Terminology

  • Schistosomiasis: a blood fluke infection.
  • Also known as:
    • Bilharzia
    • “Snail fever” — named for the snail host involved in transmission.

Causative Agents (by Region)

  • Schistosoma japonicum: endemic in Philippines and China
  • Schistosoma mansoni: in South America, Caribbean, and Africa
  • Schistosoma haematobium: endemic in Africa and the Middle East

Incubation Period

  • At least 2 months.

Mode of Transmission

  • Contact with contaminated water containing the infective larval stage.

Life Cycle / Cycle of Infection

  1. Egg release into the environment

    • An infected person urinates or defecates, releasing eggs into urine and feces.
  2. Hatching into miracidium

    • Eggs hatch into miracidium (“miracidia/miracidium”).
    • These forms are not yet harmful to humans.
  3. Snail intermediate host infection

    • Miracidium infects the snail Oncomelania quadrasi (spelled variants appear in the subtitles).
  4. Development inside the snail

    • Miracidium multiplies and matures within the snail.
  5. Release of cercaria

    • Mature forms are released as cercaria.
  6. Human infection

    • Cercaria infect humans upon contact with contaminated water.
    • Outcome: infected individuals develop schistosomiasis.

Clinical Signs and Symptoms

  • Pruritic rash / itchy rash (at the site where cercaria entered)
  • Bloody stool and/or diarrhea
  • Katayama fever
  • Fever and headache
  • Cough
  • Chills and sweating
  • Splenomegaly (enlarged spleen)
  • Hepatomegaly (enlarged liver)
  • Possible anemia (implied due to bloody stool)

Control Measures

  • Case finding
  • Health education
    • Avoid wading in potentially infected water
  • If accidentally exposed
    • Wash the exposed area with 70% alcohol
    • Alternatives mentioned: Betadine or chlorine
  • If household water is from an infected source
    • Allow water to stand for 72 hours
    • Rationale stated: cercaria die if they have no host within 48 hours; an extra 24 hours is used as precaution

Diagnostic Procedures / Tests

  • Fecal analysis
  • Liver and rectal biopsy
  • Circumoval precipitin test
    • Detects antibodies in blood indicating infection

Nursing Management

  • Hydration to prevent hypovolemia (due to diarrhea/bloody stool)
  • Antipyretic / fever care
    • Paracetamol
    • Mentions “TSB/TP sponge” (temperature-sponging method)
  • If anemia is suspected/possible
    • Diet high in iron
  • Bed rest (noted as “complete beddress,” i.e., bedridden)

Drugs Mentioned

  • Drug of choice: Praziquantel (spelled variably in subtitles)
    • Duration: 6 months
    • Dosing schedule:
      • First 3 months: two tablets per day
      • Next 3 months: one tablet per day
  • If praziquantel is not available:
    • Oxamniquine
      • For Schistosoma mansoni
    • Metrifonate
      • For Schistosoma haematobium

Endemic Regions Mentioned (Philippines, per subtitles)

  • Region 5: Bicol region
  • Region 8: Eastern Visayas (Samar and Leyte)
  • Region 11: Davao region

Researchers or Sources Featured

  • No specific researchers or external scientific sources are named in the provided subtitles.

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